Left: 77 year-old man with dysphagia, found to have an ulcerated, constricting tumor of the distal esophagus. Located several centimeters above the esophagogastric junction, this is consistent with an adenocarcinoma arising in a segment of Barrett's esophagus. Right: Esophageal metastasis: a second focus of raised, ulcerated adenocarcinoma in the distal esophagus, located 4 cm below the lesion shown above, with a segment of grossly normal esophagus between the two lesions.